ObjectiveTo evaluate the detection results of transfusiontransmitted diseases (TTD) serum markers in blood recipients before transfusion.MethodsHBsAg, HBsAb, AntiHCV, Syphilis antibody (AntiTP) and AntiHIV were detected among 102 175 blood recipients by ELISA before transfusion.ResultsAmong 102 175 patients detected, the total positive rate  of  TTD serum markers was 15.63%. The positive rate of HBsAg, AntiHCV, AntiHIV and AntiTP was 12.95%,1.11%, 0.04%  and 1.53%, respectively. The positive rate of HBsAg, HBsAb and AntiHCV in blood recipients decreased gradually from 2001 to 2007(P=0.003 or P=0.000),but the positive rate of AntiHIV tended to increase (P=0.001). ConclusionSome blood recipients have TTD before transfusion, especially HBV infection. The serology detections in patients before transfusion not only help us to avoid the medical dispute and nosocomial infection resulted from the transfusion, but also provide useful information of spread of TTD in this area.