ObjectiveTo evaluate the infection rate and prognosis in intravenous drugaddicts. MethodsSerological markers and nucleic acid of hepatitis B virus ( HBV), hepatitis C ( HCV) and human immunodeficiency virus (HIV) were detected in 48 cases of intravenous drug addicts, and clinical analysis were made.ResultsAmong 48 cases of intravenous drug addicts, double infection of HBV and HCV was 31.25%, double infection of HBV and HIV was 4.17%, triple infection of HBV, HCV and HIV was 62.50%; Hepatitis gravis accounted for 70.83%, the hospitalization time of patients with hepatitis gravis was (48.67±19.25) days, which was obviously shorter than (65.32±31.49) days of nonintravenous drug addicts with hepatitis gravis (U=4.25, P<0.01). ConclusionSuperinfection in intravenous drug addicts is high, especially hepatitis gravis, but the prognosis is better than nonintravenous drug addicts.