ObjectiveTo evaluate the requirement and identification of health care workers on responsibility of department   of hospital infection control (HIC) in general hospitals in China. MethodsRequirement and identification on responsibility of department of HIC were investigated among 453 health care workers, including hospital manager, director of department of HIC, clinical medical workers, all data were analyzed by SPSS 11.5 soft ware.ResultsIt is very similar that requirement and identification on responsibility of department of HIC among above persons in general hospitals. The requirement of HIC focus on the training for health care workers about  knowledge of hospital infection, surveillance, control and supervision of hospital infection, and personal protection, etc.ConclusionIt accords with the demand of development of infection control that requirement and identification on responsibility of department of HIC among different health care workers in general hospital in China.