铜绿假单胞菌对β内酰胺类抗生素的耐药性变迁    FREE
DOI:
作者:
作者单位:

作者简介:

周秀珍

通讯作者:

中图分类号:

R378.99+1

基金项目:


Change in drugresistance of Pseudomonas aeruginosa to βlactam antibiotics    FREE
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 文章评论
    摘要:

    目的调查某院铜绿假单胞菌对β内酰胺类抗生素的耐药性及其变迁,为临床治疗铜绿假单胞菌感染提供参考依据。方法分析1999—2007年分离的2 127株铜绿假单胞菌对18种β内酰胺类抗生素的药敏结果。结果9年来铜绿假单胞菌对18种β内酰胺类抗生素的耐药率逐年上升,各年度差异有显著性(P<0.05或P<0.01)。只有美罗培南、亚胺培南和头孢他啶的总耐药率<30%。结论铜绿假单胞菌对多种β内酰胺类抗生素耐药,且耐药率逐年增加,应适当控制第三代头孢菌素和碳青霉烯类药物的使用,以有效控制及延缓耐药株的产生。

    Abstract:

    To investigate the change in  drugresistance of Pseudomonas aeruginosa (P. aeruginosa) to βlactam antibiotics in a hospital, so as to provide reference for treatment of P. aeruginosa infection.MethodsDrug sensitivity tests of 2 127 strains of P. aeruginosa isolated fom clinic between 1999—2007 to 18 kinds of antibiotics were analysed.ResultsResistance of P. aeruginosa to 18 kinds of βlactam antibiotics  increased year by year during  the past 9 years, there was significant difference between each year (P<0.05 or P<0.01). The total resistant rates to meropenem, imipenem and ceftazidime were below 30%. ConclusionP. aeruginosa was resistant to many kinds of βlactam antibiotics, and resistant rate increased year by year, in order to control and slow down the emergence of the resistant strains , the use of third generation cephalosporins and carbapenems should be properly controlled .

    参考文献
    相似文献
引用本文

周秀珍,刘建华,孙继梅,等.铜绿假单胞菌对β内酰胺类抗生素的耐药性变迁    FREE[J]. 中国感染控制杂志,2010,9(1):43-45.
ZHOU Xiuzhen, LIU Jianhua, SUN Jimei, et al. Change in drugresistance of Pseudomonas aeruginosa to βlactam antibiotics    FREE[J]. Chin J Infect Control, 2010,9(1):43-45.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2008-09-18
  • 最后修改日期:2008-12-30
  • 录用日期:
  • 在线发布日期: 2010-01-30
  • 出版日期: