鲍曼不动杆菌肺部感染的临床特点及耐药性分析   FREE
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孙雪晈

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R563.1

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Clinical characteristics and drug resistance of Acinetobacter baumannii  pulmonary infection     FREE
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    摘要:

    目的分析和总结鲍曼不动杆菌肺部感染的临床特点及耐药规律。方法对2006年6月—2008年6月间住院的65例鲍曼不动杆菌肺部感染患者临床资料进行分析。结果鲍曼不动杆菌肺部感染在综合重症监护病房(ICU,41.54%)、神经内科监护病房(29.23%)、神经外科监护病房(10.77%)、呼吸内科(10.77%)较常见;对多种抗菌药物的耐药率>70%;感染患者大多为年老体弱、基础疾病多、住院时间长且接受各种侵入性操作、感染前反复使用2种以上抗菌药物者;部分病例合并其他病原菌感染,以铜绿假单胞菌(34.55%)及嗜麦芽窄食单胞菌(20.00%)较多。结论鲍曼不动杆菌肺部感染患者病情重,对抗菌药物耐药率高,掌握其临床特点、感染分布及耐药规律,对临床预防与治疗尤为重要。

    Abstract:

    ObjectiveTo analyze the  clinical characteristics and drug resistance of Acinetobacter baumannii (A.baumannii)  pulmonary infection. MethodsClinical data of 65 cases of A.baumannii pulmonary infections in a hospital from June, 2006 to June, 2008 were analyzed.ResultsThe incidence rate of A.baumannii infections were high in general  intensive care unit (ICU, 41.54%), neurological ICU (29.23%),  neurosurgical ICU (10.77%), and respiratory department(10.77%);Resistant rates to many kinds of antimicrobial agents were >70%.The infected patients were almost aged, with many underlying diseases, with long hospitalization time and various invasive treatment, as well as receiving  at least 2 kinds of antimicrobial agents before developing infection; some patients complicated with infections caused by the other pathogens,  most were Pseudomonas aeruginosa (34.55%) and Stenotrophomonas maltophilia(20.00%) infections.  ConclusionPatients with A.baumannii infections are in serious condition, antimicrobial  resistance is high, realization of  the clinical characteristics, infection distribution and drug resistance pattern are important to prevent and treat  infections .

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孙雪皎,王豫平.鲍曼不动杆菌肺部感染的临床特点及耐药性分析   FREE[J]. 中国感染控制杂志,2010,9(2):114-117.
SUN Xuejiao, WANG Yuping. Clinical characteristics and drug resistance of Acinetobacter baumannii  pulmonary infection     FREE[J]. Chin J Infect Control, 2010,9(2):114-117.

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  • 收稿日期:2009-04-29
  • 最后修改日期:2009-08-26
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  • 在线发布日期: 2010-03-30
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