ObjectiveTo observe the clinical effects of combination therapy of etimicin sulfate and montmorillonite powder on acute bacillary dysentery.MethodsThree hundred and twentysix patients were randomly divided into two groups: 182 patients in treatment group were  treated with combination of etimicin sulfate 0.2 g (added into 250 mL saline solution) intravenous drip for consecutive 3~5 days and montmorillonite powder orally (3 g/time, 3 times/day, the initial dose was doubled); 144 patients in control group were treated with etimicin sulfate intravenous drip with the same dose. Clinical therapeutic effect in two groups was observed.ResultsThe clinical effective rates were 93.96% (171/182) and 81.25%(171/144) in treatment and control group respectively, clinical effective rate in treatment group was significantly higher than that of control group (χ2=6.32, P<0.05); the average treatment course in treatment and control group were (2.04±0.48) and (3.12±0.71)days respectively, the former was obviously shorter than the latter(t=2.57, P<0.05) .ConclusionCombination therapy of etimicin sulfate and montmorillonite powder is an effective method for acute bacillary dysentery, and can shorten treatment course .