ObjectiveTo investigate the management level of nosocomial infection (NI) in western China.MethodsSix hospitals in 2 Chinese western provinces were surveyed, the management problems of NI were investigated, and strategies on solving these problems were put forword.ResultsSix hospitals were all established NI management departments, but only 2 provinciallevel hospitals and 1 citylevel hospital carried out catheterrelated targed surveillance; the main problems of management of key departments were lack of facilities, irrational procedure, inadequate medical instrument, incorrect disinfection and hand hygiene methods, and inadequate consciousness of occupational protection; Most hospitals participated in antimicrobial management, and use antimicrobial agents rationally.ConclusionManagement of NI in western hospitals should be intensified, the key factors of improving NI management level is hospita1 leaders’ high attention and occupation of professionals to NI.