ObjectiveTo investigate the drugresistance, drugresistant genes and prevalence of reducible clindamycin resistance of methicillinresistant Staphylococcus haemolyticus (MRSH) in Suzhou district of Anhui province.MethodsSusceptibility of 42 MRSH isolates to 16 kinds of antimicrobial agents were performed with ATB STAPH5 strip microdilute testing; drugresistant genes mecA,qacA/B/C,qacA,ermA/B/C,ermB and TetM in MRSH were detected with polymerase chain reaction; inducible clindamycin resistance was detected with Dtest.ResultsSensitive rates of 42 MRSH isolates to vancomycin and nitrofurantoin were both 100.00%, sensitive rates to rifampicin, minocycline, quinupristin/dalfopristin and teicoplanin were all >90%; resistant rates to gentamicin, norfloxacin and levofloxacin were all >70%, resistant rates to penicillin,oxacillin and erythromycin were all 100.00%. The positive rate of mecA,qacA/B/C, qacA, ermA/B/C, ermB and TetM gene was 100.00%(42 isolates), 64.29%(27), 59.52%(25), 40.48%(17), 28.57%(12) and 9.52%(4) respectively. 13 MRSH isolates were Dtest positive，30.95% of which was inducible drugresistance.ConclusionMRSH isolated from Suzhou district of Anhui province showed multidrug resistance, antimicrobial agents should be chosen rationally according to antimicrobial susceptibility testing results.