1 410例儿童呼吸道感染病原体分析
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蒋最明

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R725.6

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Analysis on pathogens in respiratory infection in 1 410 children
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    摘要:

    目的了解儿童急性呼吸道感染的病原体及其感染特点。方法选取某院2011年1—12月因急性呼吸道感染收治住院的患儿1 410例,采用直接免疫荧光法检测7种病毒(包括副流感病毒Ⅰ、Ⅱ、Ⅲ型,流感病毒A、B型,呼吸道合胞病毒和腺病毒),培养法检测细菌。分析不同月份、年龄段儿童病毒感染率及其合并细菌感染情况。结果1 410份标本中,共检出病毒阳性594份(42.13%),以呼吸道合胞病毒和腺病毒为主;检出细菌阳性258份(18.30%)。3、4、10、11月份病毒检出率较高(均>50%),7—9月病毒检出率较低(22.89%~31.40%);1~3岁组病毒检出率较高(58.04%),6~14岁组检出率较低(22.15%)。检出病毒混合感染阳性标本22份(1.56%);单一病毒感染患儿合并细菌感染157例(27.45%)。流感病毒A、B型感染组合并细菌感染率较高,分别为47.06%、47.27%。结论儿童呼吸道病毒感染率与年龄和季节均相关;病毒感染后患儿合并细菌感染率较高,其中流感病毒A、B型感染更易合并细菌感染。

    Abstract:

    ObjectiveTo realize  pathogens and infection characteristics of acute respiratory infections in children.Methods1 410 hospitalized children with acute respiratory  infection were selected from a hospital in 2011. Seven  types of viruses(parainfluenza virus Ⅰ, Ⅱand Ⅲ,Influenza virus A and B,respiratory syncytial virus  and adenovirus) were detected by direct immunofluorescence assay, bacteria were cultured.  Viral infection rate in different months, different ages, and associated infection were analyzed. ResultsOf 1 410 specimens, 594 (42.13%) were detected positive for virus, and the main viruses were respiratory syncytial virus and adenovirus; 258 (18.30%) specimens were detected positive for bacteria. Virus detection rates were high in March, April, October and November(all>50%), while low in JulySeptember (22.89%-31.40%);Virus detection rate  was high in 1-3 year age group(58.04%), while low in 6-14 year age group (22.15%). Mixed virus were detected  in 22  (1.56%) specimens, 157 children (27.45%) had coinfection of single virus and bacteria. The coinfection rate of influenza virus A or B and bacteria was 47.06% and 47.27% respectively.ConclusionRespiratory virus infection rate in children is associated with age and season. After viral infection, the associated bacterial infection is relatively higher, influenza virus A and B are more easily associated with bacterial infection.

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蒋最明,彭俊,顾敏,等.1 410例儿童呼吸道感染病原体分析[J]. 中国感染控制杂志,2013,12(2):129-131. DOI:10.3969/j. issn.1671-9638.2013.
JIANG Zuiming, PENG Jun, GU Min, et al. Analysis on pathogens in respiratory infection in 1 410 children[J]. Chin J Infect Control, 2013,12(2):129-131. DOI:10.3969/j. issn.1671-9638.2013.

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  • 收稿日期:2012-07-22
  • 最后修改日期:2012-09-12
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  • 在线发布日期: 2013-03-30
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