Abstract:ObjectiveTo study the distribution and drugresistance of multidrugresistant bacteria(MDRB) from inpatients with acquired immunodeficiency syndrome (AIDS), so as to provide reference for clinical therapy.MethodsAntimicrobial susceptibility testing result of 426 MDRB isolates from AIDS inpatients during 2009-2011 was analyzed by WHONET 5.4 software.ResultsThe isolated MDRB included 213 isolates of extendedspectrum βlactamaseproducing Enterobacteriaceae bacteria, 41 methicillinresistant Staphylococcus aureus (MRSA), 21 methicillinresistant coagulase negative Staphylococcus (MRCNS), 79 MDRAcinetobacter baumannii (MDRAB), and 72 MDRPseudomonas aeruginosa (MDRPA). Except lower drugresistance rate to a minority of broad spectrum antimicrobial agents, ESBLproducing Enterobacteriaceae bacteriaca had higher resistance rates (3.74%-100%) to other antimicrobial agents.ConclusionThe major MDRB from AIDS inpatients is Enterobacteriaceae bacteria, clinicians should choose antimicrobial agents for empirical treatment, surveillance should be intensified, so as to avoid the outbreak of MDR infection in hospital.