ObjectiveTo realize the clinical and epidemiological characteristics of measles,and explore effective measures to control measles epidemic.MethodsClinical data of 554 hospitalized measles children between January 2009 and December 2013 were analyzed retrospectively.ResultsAll children had fever,cough, and skin rash, 507 (91.52%) had typical clinical manifestations of measles, 47(8.48%) had mild manifestations; the major population were children aged≤6 months（n=176，31.77%）and 7-8 months (n=346，62.45%）;132 (23.83%) children had contact history of confirmed measles, 19(3.43%) measles children’s mothers also developed measles (all were cases of 2013）, 227 (40.97%) children had history of repeated infusion or hospitalization in large medical institutes during the measles incubation period (all were cases of 2013,there were measles children who had infusion or hospitalization in the same hospital during the same period). The peak incidence of measles usually occurs in JanuaryMay.ConclusionIntensive immunization of measles for young women of reproductive age and vaccination with “premeasles vaccine” for early infancy, and strengthening the medical management of fever outpatients are important measures to prevent measles epidemic.