ObjectiveTo understand the occurrence and risk factors for surgical site infections (SSIs) following appendectomy, so as to provide reference for taking effective prevention measures.  MethodsThrough monitoring on surgical site, SSIs in patients undergoing appendectomy in a hospital from July 1,2011 to July 1,2013 were investigated. ResultsA total of 817 appendectomy surgery patients were investigated, 37 (4.53%) of whom had SSIs, 36 of which were superficial wound infection, and 1 was deep wound infection. Univariate  analysis  showed that SSIs were related with  duration of operation, anesthesia mode,  ASA score, blood sugar, whether perioperative antimicrobials were used, and operative risk index score（all P＜0.05）. Multivariate logistic regression analysis revealed that blood sugar （OR 95% CI: 1.07-4.72）, whether perioperative antimicrobials  were used（OR 95% CI: 1.14-7.10）, and  risk index score （OR 95% CI: 5.90-43.28）were independent  risk factors for SSIs following appendectomy (all P<0.05).ConclusionSurgical site monitoring is helpful for the understanding of SSIs following appendectomy; proper intervention measures should be adopted in clinic to prevent SSIs following appendectomy.