ObjectiveTo evaluate the effect of controlling cost by introducing hand hygiene products with lower price on promoting hand hygiene compliance.MethodsThe application status and cost of hand hygiene products in 2012 was as preintervention group，2013 was as postintervention group. Effective and lower price hand hygiene products were introduced in 2013, consumption and cost of hand hygiene products before and after the intervention was compared.ResultsConsumption of hand hygiene products per patientday before and after the intervention was significantly different (［10.56±16.46］ mL vs ［13.79±16.93］ mL，Z=4.14,P<0.01); cost of hand hygiene products per patientday before and after the intervention was not significantly different (［1.23±2.07］ yuan vs ［0.92±0.59］ yuan， P>0.05).ConclusionIntroduction of hand hygiene products with lower price in this hospital can improve hand hygiene compliance to certain degree without increasing the cost of hand hygiene.