ObjectiveTo investigate risk factors for healthcareassociated infection(HAI) in patients with aneurysmal subarachnoid hemorrhage(aSAH) in the department of neurology of a hospital. MethodsClinical data of 47 patients with aSAH who were admitted to a hospital from January 2014 to January 2015 were retrospectively analyzed. ResultsOf 47 patients with aSAH, 17 developed 19 times of HAI, HAI rate was 36.17％, case infection rate was 40.43%. The main infection site was lower respiratory tract (n=17, 89.47%), followed by urinary tract (n=2,10.53%);  2 patients had both lower respiratory tract infection and urinary tract infection. 17 patients were performed pathogenic detection, 13 pathogenic isolates were isolated from 9 patients. Multivariate nonconditional logistic regression analysis revealed that risk factors for HAI in patients with aSAH were disturbance of consciousness (OR,24.878 ［95%CI, 3.996-156.040］) and intensive care unit  admission(OR,8.645 ［95%CI, 1.419-52.670］). The prognosis of patients with HAI was poorer than those without HAI（Z=4.108，P＜0.001）. ConclusionPatients with aSAH are at high risk of HAI, it is necessary to take targeted prevention and control measures for reducing the occurrence of  HAI and promoting good prognosis.