ObjectiveTo understand the development of healthcareassociated infection(HAI) management organizations in China in the past 30 years.MethodsDevelopment of HAI management organizations in 12 provinces (municipalities, autonomous regions) in China was surveyed.ResultsA total of 166 hospitals were surveyed， 96 (57.83%) were tertiary hospitals. Among 164 hospitals which had a history of development of HAI management department，46(28.05%) before 1995， 63(38.14%) in 1995-2005， and 55(33.54%) in 2005-2015 set up HAI management departments. HAI management professionals per 1 000 beds in 165 hospitals decreased from 4.80 in 1995 to 4.09 in 2015， occupational categories in HAI management departments in 1995-2015 were significantly different (χ2=26.22， P＜0.01). The constituent ratios of education background and profession of HAI management professionals in each province in 1995-2015 were significantly different（χ2=242.91,  47.10， respectively, all P＜0.01）. In 1995 and 2005,  70.81%,  53.30% of professionals were with college degree or below;  in 2015, the percentage of professionals with bachelor’s degree, doctoral degree, and master’s degree were 53.79%, 2.45%, and 22.86%  respectively. Most professionals were nursing staff，but the percentage decreased from 58.38% in 1995 to 45.96% in 2015.ConclusionAlthough HAI management organizations have developed for 30 years and made some achievements， there still remain some problems, the proportion of professionals needs to be enhanced, and personnel structure should be optimized.