ObjectiveTo understand the development history and current situation of healthcareassociated infection(HAI) management in children’s hospitals in China during the past 30 years.MethodsA retrospective survey was conducted in 20 children’s hospitals, the investigated contents included: basic situation of hospitals, HAI management organizations and professionals, the support of hospital leaders for the management of HAI, training on HAI  knowledge,  monitoring on HAI, and so on.ResultsUp to 2015, 20 hospitals all set up independent HAI management departments and HAI management committees, 46.15%（6/13） of  hospitals with more than 1 000 beds were understaffed in HAI management. There were a total of 88 professionals in HAI management in 20 children’s hospitals in 2015, 53.41% （n=47）of professionals had bachelor degree, 34.09% (n=30) were with intermediate professional title, 46.59%（n=41）were nursing staff. Up to 2015, incidences and missing report rates of  HAI,  antimicrobial usage rates, incidences of HAI in neonates all decreased compared with 2006. In 2015, 20(100.00%) hospitals all carried out monitoring on antimicrobial application, multidrugresistant organisms,  disinfection and sterilization, and provided personnel protective equipment.  In 2015, 9（45.00%）hospitals used nontouch faucets in all wards, 19（95.00%）hospitals supplied handdrying paper towel and alcoholbased hand rub in all wards. None of professionals in these hospitals participated in nationallevel  training on HAI for ≥3 times in 1996, professionals in 11 hospitals （55.00%）participated in nationallevel  training for ≥3 times in 2015.ConclusionIn the past 30 years,the management of HAI in children’s hospitals in China has basically met the requirement, monitoring on HAI gradually  improved, but allocation of HAI professionals and personnel quality ability still need to be strengthened.