Antimicrobial resistance (AMR) is increasing rapidly worldwide［1］. The European Centre for Disease Prevention and Control (ECDC) estimates that 25 000 deaths, 2.5 million extra hospital days, and 1.5 billion extra Euros are associated with AMR infection in Europe each year ［2］. In the United States, according to the Centers for Disease Control and Prevention(CDC), healthcareassociated infections (HAIs) caused by carbapenemresistant Enterobacteriaceae are responsible for 610 deaths annually［3］. Therefore, it’s urgent to prevent and control the spread of AMR.