ObjectiveTo introduce practice efficacy and achievement of medical waste management project in medical institutions.MethodsTwenty pilot medical institutions in 6 provinces and 1 520 extended medical institutions in each provinces (municipality, city) in China were selected to perform medical waste management project, the current situation of medical waste management in China was explored to develop a new feasibility plan and practice. Results“ Catalogue of medical waste classification (revised manuscript)” and “Medical waste classification collection list)” were formulated, which enhanced supervision ability of medical and health administration on medical waste management. Medical waste management training system was established, best available techniques/best environmental practices(BAT/BEP）for medical waste management were achieved, cooperation and promotion ability of medical waste management project was strengthened. ConclusionMedical waste management project has made great achievements since it is implemented in medical institutions, the achievement can be used as reference for medical waste management in China.