ObjectiveTo study the application effectiveness of standard operating procedure (SOP) video in management of minimally invasive device cleaning. MethodsStandard management began to be implemented in a hospital since January 2015, training was mainly conducted with videobased SOP lecture, defect rate of devices, qualified rate of sterilization package, and satisfaction of surgical staff before (in 2014) and after (in 2015) implementing SOP were compared, management efficacy was evaluated. ResultsAfter the implementation of SOP, device defect rate reduced from 6.19% before the implementation to 0.99%, qualified rate of sterilization package increased from 90.03% to 98.34%, satisfaction of surgical staff increased from 80.00% to 97.78%, differences were all statistically significant(all P<0.05). ConclusionThe implementation of SOP management can effectively improve the cleaning quality of surgical devices, reduce defect rate of devices, and improve the learning effect of staff, which is worth to be popularized and applied in clinical practice.