ObjectiveTo investigate risk factors for pulmonary infection(PI) in patients with acute fatty liver of pregnancy (AFLP). MethodsClinical data of AFLP patients in a tertiary hospital from January 2015 to December 2017 were analyzed retrospectively, patients with PI were in infection group, and those without PI were in control group. Age, gestational age at onset of PI, time from onset to delivery, mode of delivery, total bilirubin (TBIL), alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum creatinine (Scr), and prothrombin time (PT) were conducted univariate analysis. ResultsA total of 28 AFLP patients were collected, 10 patients who didn’t conform to the inclusion criteria were excluded, 18 AFLP patients were included, among whom 10 were with PI and 8 were control cases. Univariate analysis showed that serum TBIL level and PT in infection group were both higher than control group (P<0.05), levels of ALT and AST in infection group were lower than those in control group (P<0.05).ConclusionLiver function is a key factor affecting PI in patients with AFLP, improving liver function is the key to prevent and control PI in patients with AFLP.