ObjectiveTo analyze the registration of pulmonary tuberculosis(PTB) among students in Hunan Province, understand the epidemiological characteristics, provide evidence for improving tuberculosis control strategy in schools in Hunan Province.MethodsRegistration rate and epidemiological characteristics of students with tuberculosis in Hunan Province were analyzed through data registered in China Tuberculosis Information Management System between 2012 and 2017.ResultsFrom 2012 to 2017, 7 940 students with PTB were found in Hunan Province, the registered incidence was 13.23/1 00 000, 2 203 cases were smear positive for PTB, registered incidence was 3.67/1 00 000. Registered incidence of active PTB students in 2012-2017 was significantly different （χ2=80.079，P<0.001）；registered incidence of smear positive PTB students in 2012-2017 was significantly different （χ2=112.213，P<0.001）. The number of registered PTB students in the second quarter was the largest (32.2%), mainly male (60.8%) and students aged 15-19 years (61.8%). There was a significant difference in the registration of PTB students in different cities from 2012 to 2017 (χ2=320.432, P<0.001). The top three regions of the total number of registrations were Changsha, Xiangxi and Hengyang. From 2012 to 2017, the registered PTB students were mainly referral (38.8%), 99.8% of the patients received antituberculosis treatment, diagnosis and treatment were mainly for smearnegative, nonsevere, nondrugresistant, and newly treated patients, accounting for 67.9%, 95.2%, 99.5%, and 99.3% respectively.ConclusionIt is necessary to strengthen the prevention and control of tuberculosis in schools, screen tuberculosis among freshmen in high schools and universities, publicize tuberculosis knowledge, and improve awareness of tuberculosis prevention and control in schools.