Objective To analyze the data of imported yellow fever in acute phase as well as half a year and one-year follow-up in Beijing Ditan Hospital in 2016, so as to improve understanding of epidemic situation and treatment level of imported yellow fever. Methods Epidemiological history, etiology and clinical data of 5 patients were collected and analyzed. Results There are 5 cases of imported yellow fever, 2 of which were severe disease, 3 were mild type, 1 patient died. Severe patients had fever complicated with severe liver and kidney failure, coagulation dysfunction and so on; and mild patients were with liver and pancreatic damage, and thrombocytopenia. Mild patients recovered after half a year follow-up, and severe patients recovered after one-year follow-up. Conclusion Yellow fever is mainly caused by liver and kidney damage, it can damage heart, pancreas and other organs, even endanger life, the recovery time of liver function is long, recovery time of mild disease is half a year, severe disease needs more than one year, and the occurrence of fatty liver should be vigilant.