The epidemic of coronavirus disease 2019 (COVID-19) has brought about a great impact on society and economy, and also seriously affects the daily medical running of non-frontline departments in the fight against epidemic. This paper summarizes the relevant experience of the running of gynecological ward in Xiangya Hospital of Central South University since the outbreak of COVID-19, medical protection measures required for each link in the process of admission and treatment of patients in the gynecological ward as well as discussion and suggestion on how to apply network platform to manage the whole disease course for patients, with a view to achieving precise management for patients under the premise of medical personnel safety protection.