In order to prevent and control infection in operating rooms for patients with suspected or confirmed coronavirus disease 2019(COVID-19), according to treatment plan and technical guidelines for COVID-19 issued by National Health Commission of the People's Republic of China, as well as relevant laws and regulations of national infection prevention and control, referring to the existing experience of nursing management in operating rooms across the country, combining with the management suggestions of infection control experts in China, Expert consensus on infection prevention and control for COVID-19 suspected or confirmed patients in operating rooms in China is established. This consensus is based on the characteristics of infection prevention and control in COVID-19 patients undergoing surgery, and is elaborated from aspects of preparation before surgery, prevention and control during surgery, prevention and control after surgery, as well as other attentions, which has certain scientific and practical significance, and can provide clinical guidance for infection prevention and control of COVID-19 patients in operating rooms.