In December 2019, a novel coronavirus infection dominated by pulmonary lesions was discovered in Wuhan, Hubei Province, in February 11, 2020, World Health Organization(WHO) officially named the disease caused by novel coronavirus as coronavirus disease 2019 (COVID-19), the virus is known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 spread to the whole country in a short time, in March 11, WHO announced that COVID-19 has become a global pandemic. Laboratory test is an important basis for the confirmed diagnosis of COVID-19, which is crucial to the treatment of disease and prevention of epidemic. This paper reviews the advances in laboratory clinical diagnosis technology for COVID-19.