高毒力高耐药肺炎克雷伯菌的研究进展
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哈尔滨医科大学附属第二医院检验科, 黑龙江 哈尔滨 150086

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多丽波  E-mail: duolibo@163.com

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Advances in hypervirulent and high antimicrobial-resistant Klebsiella pneumoniae
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Department of Laboratory Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China

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    摘要:

    高毒力肺炎克雷伯菌(hvKP)已成为全球关注的病原菌,其毒力强,更易引起社区感染,患者感染hvKP后预后差、病死率高。令人担忧的是,高耐药的hvKP已经出现,对临床抗感染治疗提出了新的挑战。本文综述了hvKP的临床鉴定和主要的毒力因子,以及耐药菌株和高毒力菌株的重叠表现。

    Abstract:

    Hypervirulent Klebsiella pneumoniae (hvKP) has become a pathogen of global concern, with strong virulence, more likely to cause community-associated infection, patients infected with hvKP have poor prognosis and high mortality. What is worrying is that high antimicrobial resistance hvKP has emerged, which presenting new challenge to clinical anti-infective treatment. This paper reviews the clinical identification and major virulence factors of hvKP, as well as the overlapping expression of antimicrobial-resistant and hypervirulent strains.

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引用本文

王海日罕,多丽波.高毒力高耐药肺炎克雷伯菌的研究进展[J]. 中国感染控制杂志,2021,(11):1069-1074. DOI:10.12138/j. issn.1671-9638.20217949.
Hai-ri-han WANG, Li-bo DUO. Advances in hypervirulent and high antimicrobial-resistant Klebsiella pneumoniae[J]. Chin J Infect Control, 2021,(11):1069-1074. DOI:10.12138/j. issn.1671-9638.20217949.

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  • 收稿日期:2021-03-19
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  • 在线发布日期: 2024-04-26
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