Phages are viruses that can infect bacteria specifically and have been used to treat bacterial infections since their discovery. However, with the discovery of antibiotics and their characteristics of high efficiency, conve-nience and low cost, antibiotics are widely used all over the world, so the research on phages have been slowed down gradually. In recent years, due to the increasingly serious problem of bacterial resistance and the emergence of multidrug-resistant organisms, the search for new antimicrobial agents has become the focus and trend of anti-infection treatment. As a result, phage therapy, which has been on the verge of oblivion, attracts the attention of clinical researchers again. Based on the current research on phages at home and abroad, this paper summarizes the application of phages in the treatment of bacterial infection, and analyzes the advantages and limitations of phage therapy.