基于文献的中国军队腺病毒感染流行特征分析
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1.武警湖南总队医院防疫科, 湖南 长沙 410006;2.中南大学基础医学院寄生虫学系, 湖南 长沙 410013

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张祖萍  E-mail: zhangzp74@126.com

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Epidemiological characteristics of Human adenovirus infection in Chinese army: literature-based analysis
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1.Department of Disease Control and Prevention, Hunan Provincial Corps Hospital, Chinese People's Armed Police Force, Changsha 410006, China;2.Department of Parasitology, School of Basic Medicine, Central South University, Changsha 410013, China

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    摘要:

    目的 分析近年中国军队腺病毒感染的流行病学特征,探讨流行规律,为处置军队暴发疫情提供理论依据。 方法 从中国知网、万方和维普数据库收集1999年6月—2019年8月公开发表的中国军队腺病毒流行及暴发疫情文献,对疫情的病毒分型、暴发时间(包括年份和月份)、地区分布、人群结构和临床特征进行统计学分析。 结果 共检索到中国军队腺病毒暴发疫情有效文献44篇,包含疫情46起,共有感染病例8 710例。引发疫情的腺病毒型别包括3型(1起)、5型(2起)、7型(19起)、11型(1起)、55型(16起)和未分型(7起);其中7型和55型分别占疫情的41.3%(19起)和34.8%(16起);感染例数分别占49.5%(4 312例)和35.9%(3 129例)。1、2月和12月这三个月暴发的疫情占总疫情的76.1%(35起),感染例数占91.8%(7 999例);发病人群主要以新兵或学兵为主,占全部人群的89.2%(2 504/2 807);临床表现主要为发热、咳嗽、咽痛和咽部充血等;7型和55型腺病毒感染最常见,且易出现重症化倾向。 结论 中国军队腺病毒感染以7型和55型最常见,在新兵或学兵集训的冬春季节,应加强腺病毒感染防控工作,防止出现腺病毒感染暴发疫情。

    Abstract:

    Objective To analyze the epidemiological characteristics of Human adenovirus(HAdV) infection in Chinese army in recent years, and explore the epidemic trend, so as to provide theoretical basis for the disposal of military epidemic outbreaks. Methods Literatures on epidemic outbreak of HAdV in Chinese army published from June 1999 to August 2019 were collected from China National Knowledge Infrastructure (CNKI), Wanfang Database and VIP Database. Virus typing, outbreak time (including year and month), regional distribution, population structure and clinical characteristics were analyzed statistically. Results A total of 44 available literatures on HAdV epidemic outbreaks in Chinese army were retrieved, including 46 events of epidemic outbreaks involving 8 710 cases of infection. The types of HAdV causing the epidemic included type 3 (1 event), type 5 (2 events), type 7 (19 events), type 11 (1 event), type 55 (16 events) and unclassified type (7 events); type 7 and type 55 accounted for 41.3% (19 events) and 34.8% (16 events) respectively; the number of infection accounted for 49.5% (4 312 cases) and 35. 9% (3 129 cases) respectively. The outbreaks in January, February and December accounted for 76.1% (35 events) of the total outbreaks, and the number of infection cases accounted for 91.8% (7 999 cases); the main population with infection were recruits or cadets, accounting for 89.2% (2 504/2 807) of the total population; the main clinical manifestations were fever, cough, sore throat and pharyngeal congestion; type 7 and type 55 HAdV infection were the most common, which was prone to be severe. Conclusion Type 7 and type 55 are the most common types of HAdV infection in Chinese army, during training of recruits or cadets in winter and spring, prevention and control of HAdV infection should be strengthened to prevent the outbreak of HAdV infection.

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章保新,简明,袁桔华,等.基于文献的中国军队腺病毒感染流行特征分析[J]. 中国感染控制杂志,2021,(3):198-204. DOI:10.12138/j. issn.1671-9638.20217216.
Bao-xin ZHANG, Ming JIAN, Ju-hua YUAN, et al. Epidemiological characteristics of Human adenovirus infection in Chinese army: literature-based analysis[J]. Chin J Infect Control, 2021,(3):198-204. DOI:10.12138/j. issn.1671-9638.20217216.

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  • 收稿日期:2020-04-20
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  • 在线发布日期: 2021-07-26
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