Objective To explore the value of intelligent endoscope storage cabinet and standard endoscope storage cabinet in drying digestive endoscope lumen. Methods 240 endoscopes were divided into 30 seconds (30 s), 40 s, and 50 s inflation groups according to the time required to inflate the biopsy lumen with pressure air gun, with 80 pieces in each group. After the completion of inflation, 13, 30, 41 pieces of dried endoscopes were excluded from the 30 s, 40 s, and 50 s inflation groups, drying unqualified endoscopes in each group were divided into trial group and control group by random number method, endoscopes in trial group and control group were placed in intelligent and standard endoscope storage cabinet respectively. When endoscopes were placed for 1, 2, 3, 6, and 24 hours, the moisture test was performed to detect whether the lumen contained residual droplets. Results The qualified rates of endoscopic lumen drying in 30 s, 40 s and 50 s inflation groups were 16.25%, 37.50% and 51.25% respectively, difference among three groups was significant (P < 0.05). After endoscopes in inflation groups were placed in the storage cabinet for 1, 2, 3 and 6 hours, there was significant difference in the qualified rate of endoscopic lumen drying between intelligent cabinet and standard cabinet (both P < 0.05). Lumen of all reprocessed endoscopes could achieve complete drying when endoscopes were placed in intelligent cabinet for 1 hour. When endoscopes in 30 s and 40 s inflation groups were placed for 24 hours, qualified rate of lumen drying between intelligent cabinet and standard cabinet was still significantly different (both P < 0.05), when endoscopes in 50 s inflation group were placed for 24 hours, qualified rate of lumen drying between intelligent cabinet and standard cabinet was no significantly different (both P>0.05). Conclusion Intelligent cabinet is beneficial to the rapid drying of endoscope lumen and reduces the risk of microbial growth, which is worthy of popularization and application.