Objective To evaluate the disposal and management status of loaner medical instruments and implants in central sterile supply department(CSSD)of China, provide data support for standardizing the disposal and mana-gement of loaner medical instruments and implants, prevent and control the risk of healthcare-associated infection. Methods Literatures on the disposal and management status of loaner medical instruments and implants in Chinese hospitals between January 2008 and August 2021 were retrieved from China National Knowledge Infrastructure (CNKI), Wanfang Data, VIP, China Biology Medicine disc (CBM) and PubMed, literatures were screened and data were extracted strictly according to the inclusion and exclusion criteria, Stata 16.0 software was adopted for Meta-analysis. Results A total of 12 literatures involving 2 769 hospitals were included in the study. The combined results of Meta-analysis showed that the implementation rate of the management and disposal system of loaner medical instruments and implants was 90% (95%CI: 84%-96%), implementation rate of professional training was 68% (95%CI: 48%-89%), implementation rate of CSSD as receiving location was 58% (95%CI: 42%-75%), implementation rate of delivery one day before operation was 68% (95%CI: 54%-82%), implementation rate of cleaning and disinfection in CSSD after operation was 48% (95%CI: 20%-75%), implementation rate of correct sterilization procedures and parameters provided by manufacturers was 54% (95%CI: 27%-81%), and the implementation rate of special post responsibility was 63% (95%CI: 41%-86%). Conclusion There are still some problems in the disposal and management of loaner medical instruments and implants in Chinese hospitals, such as low implementation rate of special post responsibility system, inadequate training of professionals, low implementation rate of cleaning and disinfection in CSSD after operation, and correct sterilization procedures and parameters are not provided by some manufacturers. It is still necessary to standardize the disposal and management system, refine the disposal process and quality control details, and strengthen professional training.