Objective To understand the consumption of hand hygiene(HH) products and HH compliance in intensive care units (ICUs) of secondary and higher grade medical institutions (MIs) in Shanghai, and provide basis for further monitoring of HH among health care workers (HCWs). Methods Through healthcare-associated infection surveillance system, the consumption of HH products and HH compliance in ICUs from secondary and higher grade MIs in Shanghai in 2017-2021 were analyzed. Results 105 ICUs from 74 MIs were included in analysis, the average consumption of HH products was 79.24 (44.88-258.63) mL/(bed·day), with statistically significant difference among different types of ICUs (P < 0.001). The average consumption of HH products increased from 65.75 mL/(bed·day) in 2017 to 87.55 mL/(bed·day) in 2021, showing an increasing trend year by year (P < 0.001). HCWs' HH compliance rate was 82.13%, with the highest in nurses (86.59%) and the lowest (48.90%) in medical technicians, HH compliance rates of HCWs of different occupations were statistically significant different (P < 0.001). Among the implementation modes of HH, 39.86% used running water for hand washing, 42.27% used alcohol-based hand rub to wipe hands, 13.22% didn't take HH measures, and 4.65% didn't take HH mea-sures when wearing gloves, with statistically significant differences among different HH implementation modes of HCWs (P < 0.001). There was a positive correlation between the average consumption of HH products per bed·day and HCWs' HH compliance rate (r=0.703, P < 0.05). Conclusion The average consumption of HH products per bed·day and HH compliance rate of HCWs in ICUs in Shanghai presents an increasing trend year by year. There are differences in the average consumption of HH products per bed· day and HH compliance rate among different types of ICUs. The implementation of HH can be evaluated by continuously surveillance on the average consumption of HH products per bed·day.