Objective To investigate the clinical characteristics of inguinal abscess caused by Actinotignum schaalii (A. schaalii), and improve the clinical recognition and attention on skin and soft tissue infection caused by this bacterium. Methods Clinical data of a patient with inguinal abscess caused by A. schaalii were reviewed. Biological characteristics of the bacterium were observed, and antimicrobial susceptibility testing was conducted. PubMed database was retrieved using "Actinobaculum schaalii" and "Actinotignum schaalii" as keywords. Meanwhile, China National Knowledge Infrastructure, Wanfang, and VIP databases were retrieved using corresponding Chinese retrieval terms. Clinical data of skin or soft tissue infections caused by A. schaalii were summarized and analyzed. Results After literature retrieval and screening, 38 cases from 13 literatures were finally included, out of which 33 patients with A. schaalii infection were treated with antimicrobial agents and/or incision drainage, and the treatment effect was good. Conclusion A. schaalii is an opportunistic pathogen. There are few reports on skin or soft tissue infections caused by it. Currently, the identification of this bacterium relies on mass spectrometry technology or gene sequencing. Clinical attention should be paid to the detection of this bacterium, and appropriate antimicrobial agents should be selected for its treatment.