Pulmonary nocardiosis is a pulmonary infectious disease caused by Nocardia, it is commonly occurred in immunocompromised hosts and patients with structural pulmonary diseases, the clinical manifestations are similar to those of pneumonia caused by other pathogens, and a confirmed diagnosis requires pathogenic evidence. Influenza can affect the lower respiratory tract and cause secondary bacterial pneumonia, but secondary pulmonary nocardiosis has rarely been reported. This paper reports the clinical data of two patients with pulmonary nocardiosis secondary to influenza, summarizes the clinical manifestations, diagnosis and treatment process, and prognosis, with the aim to enhance clinicians’ understanding on this disease.