ObjectiveTo explore HIVinfected people coinfected with HCV or TB in Hunan Province, and assess the incidence and related factors. MethodsHIV infected inpatients and outpatients in local hospitals in Hunan Province between 2006 and 2008 were surveyed by questionnaires, existing cases of HIV infected persons were performed detection of HCV and TB antibody; HIV and HCV or TB coinfection were analysed statistically  with SPSS software. ResultsA total of 978 cases were investigated, HIV and HCV coinfection rate was 33.95% (332 cases). The coinfecion rate of HIV and HCV in intravenous drug user, persons at the age of 30-44 and the jobless persons was  81.06% (321/396), 42.60%(262/615)and 61.89% (302/488) respectively; coinfection rate of HIV and HCV  in above three groups were  all higher than the other related groups （P＜0.0125，＜0.0125，＜0.0045）. Infection rate of HIV combined TB was 26.99% (264/978), coinfection rate in intravenous drug users(35.86%) was obviously higher that (19.65%)  in patients through sex（P＜0.0071）. Coinfection rate of HIV and TB in patients with CD4+T cell count ≤ 200/ μL was 41.59%, which was higher than that in other groups （both P＜0.0125）. ConclusionIt is the initial report on state and related factors of  HIV combined with  HCV or TB coinfection. Intravenous drug use is the most principal way for HIVinfected patients infect with HCV. Patients for HIV/HCV coinfection are concentrated on the age of 30-44 years old and the jobless. The incidence of tuberculosis in  HIV patients with CD4 + T cell count ≤200 / μL is higher than other HIV patients.