ObjectiveTo analyze the  clinical characteristics and drug resistance of Acinetobacter baumannii (A.baumannii)  pulmonary infection. MethodsClinical data of 65 cases of A.baumannii pulmonary infections in a hospital from June, 2006 to June, 2008 were analyzed.ResultsThe incidence rate of A.baumannii infections were high in general  intensive care unit (ICU, 41.54%), neurological ICU （29.23%）,  neurosurgical ICU (10.77%), and respiratory department(10.77%);Resistant rates to many kinds of antimicrobial agents were >70%.The infected patients were almost aged, with many underlying diseases, with long hospitalization time and various invasive treatment, as well as receiving  at least 2 kinds of antimicrobial agents before developing infection; some patients complicated with infections caused by the other pathogens,  most were Pseudomonas aeruginosa (34.55%) and Stenotrophomonas maltophilia(20.00%) infections.  ConclusionPatients with A.baumannii infections are in serious condition, antimicrobial  resistance is high, realization of  the clinical characteristics, infection distribution and drug resistance pattern are important to prevent and treat  infections .