ObjectiveTo realize the characteristics of nosocomial infection management of mine disaster miners during medical rescue.MethodsOn the spot investigation were performed  in the hospitals where the mine disaster miners were cured,  infection control measures were put forward , the effect of these measures was evaluated  and adjusted timely according to the patients’ condition.ResultsThere was no nosocomial  infection occurring in the mine disaster miners,  successful medical rescue was ensured. ConclusionThe enforcement of infection control measures are appropriate and  effective.