ObjectiveTo explore healthcareassociated infection(HAI) and risk factors in elderly lung cancer patients.MethodsMedical data of lung cancer patients aged≥60 years in a tumor hospital between May 2006 and May 2011 were analyzed retrospectively.ResultsOf 324 patients,63 (19.44%) developed HAI,the major pathogens were gramnegative bacilli (37 isolates, 58.73%), the next were grampositive cocci (20 isolates, 31.75%), fungi accounted for 9.52% (6 isolates); the main infection sites were respiratory tract and oral cavity,the constituent ratio was 47.62%(30 cases) and 17.46%(11 cases) retrospectively. Univariate analysis revealed that the stage of TNM, invasive operation, antitumor therapy, smoking and associated underlying diseases were related risk factors for HAI in elderly patients with lung cancer(P<0.05).ConclusionHAI in elderly lung cancer patients is high, prevention and control should be taken according to related risk factors.