ObjectiveTo evaluate the effectiveness of healthcareassociated infection(HAI) monitoring team on preventing ventilatorassociated pneumonia (VAP) in patients undergoing mechanical ventilation in an intensive care unit(ICU).MethodsFrom January to December, 2011, 480 ICU patients receiving mechanical ventilation for >48 hours were studied. Patients were divided into two groups, control group included 233 patients who admitted to ICU between January and June received VAP prevention bundle, but without being monitored by HAI monitoring team; intervention group included 247 patients who admitted to ICU between July and December received routine preventive measures and were supervised the implementation of VAP prevention measures by HAI monitoring team. The elevation rate of the head of bed, incidence of VAP, duration of mechanical ventilation and mortality in two groups were compared and analyzed.ResultsThe elevation rate of the head of bed of intervention group was significantly higher than control group (93.79% vs 61.11‰, χ2=703.43, P<0.001）; duration of mechanical ventilation in intervention group was significantly lower than control group (［5.56±4.43］d vs ［6.87±6.76］d, t=2.49，P=0.013）; the incidence of VAP in intervention group was significantly lower than control group (11.00‰ vs 24.62‰, χ2=6.87, P=0.009）; there was no significant difference in mortality of two groups （6.07% vs 9.44%, χ2=1.91，P=0.142）.ConclusionThe preventive measures of VAP can be carried out effectively by the strict supervision of infection monitoring team, VAP can decrease through effective work of infection monitoring team.