ObjectiveTo analyze the epidemiological and clinical characteristics of measles cases, and compare the differences between adult and infant measles. MethodsClinical data of 165 measles patients hospitalized between January 2006 and June 2013 were analyzed retrospectively, epidemiological and clinical characteristics between infant and adult measles were compared.ResultsExcept December, measles occurred all the year round, and mostly occurred between February and August (157 cases, 95.15%).The occurrence of high fever（n=68，82.93%）,Koplik’s spot（n=78，95.12%）,gastrointestinal symptoms（n=43， 52.44%）,eye symptoms（n=61， 74.39%）in adult group were higher than infant group(［n=39， 55.71%］,［n=47， 67.14%］,［n=23， 32.86%］,［n=41， 58.57%］,respectively), duration of Koplik’s spot in adult group was longer than infant group(［5.99±1.57］d vs［3.12±1.41］d)，(all P<0.05）, incidence of abnormal liver function in adult group was significantly higher than infant group(［n=64， 78.05%］vs［n=7， 10.00%］）,while incidence of bronchopneumonia in infant group was higher than adult group（［n=29， 41.43%］ vs ［n=12， 14.63%］）(both P＜0.05）.Of 32 adults who were performed detection of lymphocyte count on the second day of admission, 30(93.75%) were had decrease of absolute CD4+T lymphocyte count (［122.10±96.20］cells/μL)，repeated detection after oneweek treatment showed an elevated CD4+T lymphocyte count （［445.10±187.20］cells/μL） in 26 adults（P＜0.01）.ConclusionAdult measles is more likely to appear high fever, gastrointestinal symptoms, eye symptoms and liver injury, systemic symptoms are serious; while infant measles is more likely to appear bronchopneumonia.