ObjectiveTo explore the risk factors for healthcareassociated infection (HAI) caused by Candida in a hospital.Methods64 patients with healthcareassociated(HA) Candida infection in a hospital between January 2011 and October 2013 were selected as case group, and 64 patients without HA Candida infection during the same period were as control group, clinical data of two groups of patients were analyzed.ResultsThe main Candida causing HAI were Candida albicans（68.75%）,followed by Candida tropicalis（15.62%）, Candida glabrata (9.38%) and Candida krusei （6.25%）.The major infection sites were respiratory tract（67.19%），urinary tract（18.75%） and digestive tract(10.94%）. Univariate analysis showed the risk factors for HA Candida infection were age, length of hospital stay, diabetes, and malignant tumor and so on; multivariate logistic regression analysis showed that important risk factors for HA Candida infection were age（OR 95% CI：2.57-33.67）, length of hospital stay（OR 95% CI：2.17-25.37）,malignant tumor（OR 95% CI：1.04-15.23）,chemotherapy（OR 95% CI：1.76-20.63）, and use of respirator（OR 95% CI：4.67-96.37）.ConclusionRisk factors for HA Candida infection are complicated, in order to reduce the incidence of HA Candida infection,risk factors should be considered, and preventive measures according to risk factors should be made.