ObjectiveTo evaluate the correlation between serum procalcitonin concentration and systemic inflammatory response syndrome (SIRS) score in patients with bacterial bloodstream infection.MethodsIn JanuaryDecember, 2012, 96 patients with bacterial bloodstream infection in a hospital were selected as trial group, and these patients were divided into three groups(group A,B and C) according to SIRS score; 84 patients without bacterial infection was as control group, PCT concentration of all patients were detected, and the correlation between PCT concentration and SIRS score was analyzed. ResultsAmong 96 patients with bacterial bloodstream infection,7 （7.29%）died (4 were in group B and 3 in group C); there was no death case in control group. PCT concentration in control group, group A,B and C of trial group were （0.28±0.09）ng/mL,（0.63±0.13）ng/mL,（3.68±1.01）ng/mL, and（7.45±1.53）ng/mL，respectively, the difference between each group was significant（P＜0.01）. Pairwise comparison of four groups showed statistical difference (P＜0.001）.Spearman correlation analysis on PCT concentration and SIRS score was conducted, correlation coefficient r=0.874（P＜0.001）suggested positive correlation between serum PCT concentration and SIRS score.ConclusionPCT concentration in patients with bacterial bloodstream infection and SIRS score is positively correlated, PCT concentration and SIRS score can be used as two markers for assessing the extent and prognosis of bacterial bloodstream infection.