Abstract:ObjectiveTo investigate antimicrobial use in 33 township central hospitals, and improve the rational use of antimicrobial agents. MethodsThirtythree township central hospitals in 11 counties were randomly selected, 7 920 outpatient prescriptions, medical records of 465 nonsurgery patients and 213 surgery patients were investigated and analyzed. ResultsOf 33 hospitals, antimicrobial usage rate in outpatients and inpatients was 56.60% and 89.68% respectively,combined antimicrobial usage rate was 24.16% and 43.58% respectively. Antimicrobial use density in inpatients was 147.25DDDs. Antimicrobial usage rate in surgery patients was 97.18%, combined antimicrobial usage rate was 59.90%,the percentage of one drug, twodrug combination and threedrug combination was 40.10%, 47.82%, and 12.08% respectively. The percentage of antimicrobial use in patients of type Ⅰ,Ⅱ,and Ⅲincision was 97.56%(40/41), 96.93%(158/163) and 100.00%(9/9)respectively,combined antimicrobial usage rate was 30.00%,67.72%, and 44.44% respectively.ConclusionThe overuse of antimicrobial agents exists in 33 township central hospitals, antimicrobial usage rate, combined usage rate, antimicrobial use density and antimicrobial prophylaxis in typeⅠincision operations are all high.