ObjectiveTo explore the incidence of surgical site infection (SSI) and  compliance to bundled intervention measures, and evaluate the effect of bundled interventions on controlling SSI.MethodsFrom October 2013 to September 2014, three types of surgeries (colorectal surgery, abdominal hysterectomy, and femoral neck repair surgery) in 29 hospitals in China were monitored, October 2013 to March 2014 was baseline investigated stage, April 2014 to September 2014 was intervention stage. ResultsA total of 6 166 episodes of surgeries  were monitored, the incidence of SSI was 1.64%, incidence of  SSI following colorectal surgery, abdominal hysterectomy, and femoral neck repair surgery were 4.47%, 1.03%, and 0.21% respectively. The P75 time of three types of surgeries were 3, 2, and 2 hours respectively.Compared with the baseline stage， the compliance to most intervention measures improved after intervention, the largest increase in the compliance to interventions was  disinfection with chlorhexidinecontaining disinfectant at surgical sites of colorectal surgery (increased by 29.09%), followed by preoperative shower of femoral neck repair surgery (increased by 26.24%), preoperative shower  of colorectal surgery(increased by 22.95%),  and skin preparation on the day of operation (increased by 20.75%). Incidences of SSI in three types of surgeries were not significantly different before and after intervention(all P＞0.05).ConclusionThe incidences of SSI are different among different types of surgeries，the compliance to most bundled intervention measures has improved to some extent after intervention, but effectiveness of intervention measures needs to be further observed.