ObjectiveTo understand the occurrence of catheterassociated urinary tract infection(CAUTI) in patients with  catheterization, and provide evidence for reducing the incidence of CAUTI. MethodsBased on monitoring requirement for  CAUTI in competency building project of healthcareassociated infection(HAI) prevention and control established by Hospital Infection Management Committee of Chinese Hospital Association, CAUTI among patients who hospitalized and received urinary catheterization ≥2 days in a hospital from January to December 2014 were analyzed prospectively, incidences of CAUTI in different patients were compared. ResultsA total of 6 046 patients with  urinary catheterization were monitored, 166 of whom developed CAUTI， incidence of CAUTI was 2.75%, the total urinary catheter days were  31 833 days, incidence of CAUTI was 5.21 per 1 000 urinary catheter days. There was no significant difference in the incidence of CAUTI among patients of different genders （χ2=1.23，P=0.54）；incidence of CAUTI in patients ＞ 60 years old was higher than those ≤60 years （4.72%  vs 2.07%, χ2=30.38，P＜0.01）；incidence of CAUTI in patients with different duration of catheterization was significantly different（χ2= 251.14，P＜0.01）；with the prolongation of  duration of catheterization, incidence of CAUTI also increased（trend  χ2=211.82，P＜0.001）.Patients in department of neurology had the longest average catheterization time（14.84 days）and highest incidence of CAUTI（15.00%, 10.11‰）；patients in the other departments of surgery  had the shortest average catheterization time（3.56  days）and lowest incidence of CAUTI（0.97%,2.74‰）；incidences of CAUTI in patients with urinary catheterization in different departments were significantly different（χ2= 302.24，P＜0.001）. 166 CAUTI patients were isolated 66 isolates of pathogenic strains, 86.36% were gramnegative bacilli, 33.33%  of which were Escherichia coli. ConclusionCAUTI is related to the age of patients and duration of indwelling urinary catheter. Daily assessment on the necessity of indwelling catheter and timely removal of catheter is helpful for reducing the occurrence of CAUTI.