ObjectiveTo investigate the current situation of healthcareassociated infection(HAI) organization management systems in primary medical institutions.Methods95 primary medical institutions in 5 provinces (autonomous regions, municipalities) in China were investigated.ResultsOf 95 primary medical institutions，82(86.32%) established HAI management groups, 65 (68.42%) set up antimicrobial management departments, 87(91.58%) assigned professionals  for antimicrobial management. Before 2010, only 26 antimicrobial management departments were set up, which  increased to 65（68.42%）in 2015. Hospitals established rules and regulations on medical waste management (n=93, 97.89%）, disinfection and sterilization(n=87, 91.58%）, disposable sterile medical device (n=87, 91.58%）, HAI prevention and control measures (n=79, 83.16%）, occupational health and safety protection for health care workers(n=76, 80.00%）,outbreak reporting system (n=73, 76.84%）, hand hygiene (n=69, 72.63%）, and monitoring on HAI (n=56, 58.95%).ConclusionCurrent situation of HAI organization management systems in primary medical institutions needs to be improved, health administrative departments should strengthen supervision to improve the level of HAI prevention and control.