ObjectiveTo understand current situation of fulltime healthcareassociated infection(HAI) management staff in hospitals in Xianyang, explore the causes of instability of HAI management team. MethodsStratified random sampling method was adopted, hospitals were divided into secondary and tertiary levels, then numbered according to different levels, surveyed hospitals were selected randomly, general condition, professionals, and causes of instability of 52 selected fulltime HAI management staff members in 29 secondary and above hospitals in Xianyang were surveyed. ResultsFulltime HAI management staff were mainly women, accounting for 89.13%; 54.35% of staff were aged 30-50 years; 47.83% had bachelor degree and above; 41.30% had intermediate professional titles; 65.22% were nurses；91.30% engaged in HAI management for <9 years; HAI management staff were statistically different in age and education level（both P<0.05）. 63.04% of fulltime HAI management staff engaged in nursing before engaging in HAI management work; 63.04% engaged in HAI management work according to administrative arrangement, the top three causes for instability of HAI management team were heavy workload（91.30%）, lacking enough attention of leaders（78.26%）, and low pay（63.04%）. ConclusionStructure of HAI management fulltime staff in hospitals in Xianyang is irrational, the main causes for unstable management team is heavy workload, insufficient attention paid by leaders, and low pay.