ObjectiveTo analyze the medical environmental distribution characteristics of carbapenemresistant Klebsiella pneumoniae (CRKP).MethodsOn April 25 and August 29, 2016, random sampling was performed before cleaning and disinfecting the surrounding of patients who isolated CRKP in a hospital, sampling were mainly object surfaces and medical devices. Distribution characteristics of CRKP were analyzed. ResultsThe number of environmental sampling in surgical intensive care unit(SICU), respiratory ICU(RICU), and emergency ICU(EICU) were 90, 41， and 56 respectively. CRKP was not found in SICU and RICU specimens; 6 strains of CRKP were isolated in EICU, the isolation rate was 10.71%. In April 2016, 103 specimens were taken, and 6 strains of CRKP were isolated, isolation rate was 5.83%, which was higher than in August of 2016(P<0.05). There were no significant differences in isolation rates of CRKP among different specimens and different responsible persons (all P>0.05). ConclusionKey departments, such as EICU, should be intensified cleaning and disinfection, so as to reduce the spread of CRKP in the medical environment.