ObjectiveTo systematically evaluate the compliance and correct rate of hand hygiene(HH) among doctors and nurses in secondary and above hospitals in mainland China，and provide data support for HH promotion. MethodsLiteratures about study on HH in mainland China after 2015 were retrieved from Chinese and English databases, researchers evaluated the literatures according to the relevant standards, screened the qualified literatures and extracted the data strictly according to the inclusion and exclusion criteria, Meta analysis was adopted to analyze the compliance and the correct rate of HH of doctors and nurses in different levels of hospitals and at different departments.ResultsThe overall compliance rate of HH of nurses was higher than doctors, compliance rates of HH of doctors and nurses were 55.9% (95%CI: 45.9%, 65.8%) and 66.0%(95%CI: 58.8%, 73.1%） respectively；HH correct rates of doctors and nurses were 65.2% (95%CI: 53.6%, 76.9%) and 67.9%(95%CI: 56.9%, 78.9%) respectively. Compliance rates of HH of doctors and nurses in tertiary hospitals were both higher than secondary hospitals, compliance and correct rates of HH of doctors and nurses in intensive care unit were both higher than general departments.ConclusionThe compliance and correct rate of HH in mainland China need to be further improved, especially the promotion in primary hospitals and general departments.