ObjectiveTo explore the application of bundle management in the prevention of catheterassociated urinary  tract infection (CAUTI) in stroke patients, so as to reduce the incidence of CAUTI in stroke patients. MethodsStroke patients who were admitted to the department of neurology of a hospital and with indwelling urinary catheter between January 2016 and May 2017 were selected, patients who were admitted between January and August 2016 were as control group (adopting routine urinary catheter maintenance method), between September 2016 and May 2017 were as trial group (adopting bundle management measures). The implementation rate of urinary catheter maintenance measures, urinary catheter indwelling time, urinary catheter contamination rate, and incidence of CAUTI were compared between two groups of patients.ResultsA total of 60 patients were enrolled in the study, 30 were in control group, and 30 in trial group. The implementation rate of catheter maintenance measures in trial group was higher than that in control group (92.55% vs 71.74%, P=0.000). The implementation rates of catheter maintenance measures in trial group on the third, tenth, and seventeenth day were 94.64%, 89.13%, and 91.30% respectively, and control group were 78.55%, 67.87%, and 54.89% respectively, there were significant difference between two groups (both P<0.05). Catheter indwelling time in trial group was shorter than control group (［9.67±3.54］ d vs ［12.40±6.52］ d, P<0.05); contamination rate of urinary catheter in trial group was lower than control group (13.33% vs 50.00%, P<0.05); incidence of CAUTI in trial group was lower than control group (3.33% vs 26.67%, P＜0.05）. ConclusionBundle management can improve the implementation of urinary catheter maintenance measures, establish feedback mechanism, continuously improve quality, combined with bladder function training and rehabilitation, it can shorten catheter indwelling time, reduce urinary catheter contamination, and reduce the incidence of CAUTI in patients.