Objective To observe the damage of disposable non-woven fabric used for packing device, analyze the causes of damage of packing, and improve the integrity of package by improving the packing method. Methods From October 2017 to December 2018, 5 000 surgical device packages of the same specification in a hospital were selected as the research objects, and divided into groups A-E according to different packing methods (group A:common basket+disposable non-woven fabric; group B:common basket+disposable absorbent liner+disposable non-woven fabric; group C:flat bottom basket+disposable non-woven fabric; group D:flat bottom basket+disposable absorbent liner+disposable non-woven fabric; group E:basket+flat bottom basket+disposable absorbent liner+disposable non-woven fabric), each group has 1 000 pieces. Damage of device packing at 7 steps from the completion of packing to pre-use was observed and recorded (① completing packing; ② loading to sterilization rack; ③ unloading to storage rack after sterilization; ④ loading into transport vehicle; ⑤ unloading to storage rack in operating room; ⑥ placing on manipulating platform before use; ⑦ openning before use). Results Damage rates of packing in group A-E were 21.7%, 13.5%, 8.8%, 5.2%, and 0.1% respectively, the highest was in group A and the lowest in group E, differences were all statistically significant (all P<0.001). In transfer step ①-⑦, damage rates of packing were 0, 0.24% (n=12), 1.04% (n=52), 1.44% (n=72), 3.44% (n=167), 0.30% (n=15) and 0.46% (n=23) respectively, except that the number of packing damage of step ① was 0, packing damage ccurred in other steps, and step ⑤ had the highest damage rate, damage of device package occurred continuously until it was pre-used in departments. Conclusion Compared with common basket, damage rate of device packing with flat bottom basket is lower, the use of disposable absorbent paper can further protect the packing from damaging, transport basket can effectively reduce the damage of packing in the process of transportation.